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The antibody against DCP1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 386-617 of human DCP1B (NP_689853.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DCP1B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 386-617 of human DCP1B (NP_689853.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-07381A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DCP1B |
| Target Synonyms | DCP1; DCP1B | Form | Liquid |
| Species Reactivity | Human, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 386-617 of human DCP1B (NP_689853.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8IZD4 | Immunogen Sequence |
Uniprot Id
Q8IZD4
Target Species
Human
Target Name
DCP1B
Target Full Name
mRNA-decapping enzyme 1B
Target Function
May play a role in the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. May remove the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP.
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
DCP1 family
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
DCP1B; mRNA-decapping enzyme 1B
Target Background
This gene encodes a member of a family of proteins that function in removing the 5' cap from mRNAs, which is a step in regulated mRNA decay. This protein localizes to cytoplasmic foci which are the site of mRNA breakdown and turnover. Alternative splicing results in multiple transcript variants.
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