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The antibody against DCTN3 was raised in rabbit using the Recombinant Human Dynactin subunit 3 protein (2-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DCTN3 was raised in rabbit using the Recombinant Human Dynactin subunit 3 protein (2-176AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human brain tissue using DCTN3 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human pancreatic tissue using DCTN3 Antibody at dilution of 1:1002
| Cat.No | ADC-44986A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DCTN3 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dynactin subunit 3 protein (2-176AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75935 |
Uniprot Id
O75935
Target Species
Human
Target Name
DCTN3
Target Full Name
Dynactin subunit 3
Target Function
Together with dynein may be involved in spindle assembly and cytokinesis.
Target Subcellular Location
Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Cleavage furrow. Midbody. Note=Localizes to punctate cytoplasmic structures and to the centrosome during interphase, and to kinetochores and to spindle poles throughout mitosis. Colocalizes with dynein to the cleavage furrow and to midbody of dividing cells.
Target Protein Families
Dynactin subunit 3 family
Target Tissue Specificity
Ubiquitously expressed. Highly expressed in muscle and pancreas and detected at lower levels in brain.
Target Research Area
Cell Cycle
Target Synonyms
DCNT22; DCTN 22; DCTN22; Dctn3; DCTN3_HUMAN; dynactin 3 (p22); dynactin 3; dynactin 3 isoform 1; Dynactin complex subunit 22 kDa subunit; dynactin light chain; Dynactin subunit 3; p22
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