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Rabbit anti-Human DDHD2 Polyclonal Antibody

The antibody against DDHD2 was raised in rabbit using the Recombinant Human Phospholipase DDHD2 protein (361-650AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-25079A

The antibody against DDHD2 was raised in rabbit using the Recombinant Human Phospholipase DDHD2 protein (361-650AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-25079A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDDHD2
FormLiquidSpecies ReactivityHuman, Rat
IsotypeIgGStorage Buffer0.02% sodium azideConstituents: PBS containing 50% glycerol
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Phospholipase DDHD2 protein (361-650AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO94830
Background Information
  • Uniprot Id

    O94830

  • Target Species

    Human

  • Target Name

    DDHD2

  • Target Full Name

    Triacylglycerol hydrolase DDHD2

  • Target Function

    Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane.

  • Target Involvement

    Spastic paraplegia 54, autosomal recessive (SPG54)

  • Target Subcellular Location

    Cytoplasm, cytosol. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.

  • Target Protein Families

    PA-PLA1 family

  • Target Tissue Specificity

    Widely expressed (at protein level).

  • Target Synonyms

    DDHD domain containing protein 2; DDHD domain-containing protein 2; Ddhd2; DDHD2_HUMAN; KIAA0725; mKIAA0725; Phospholipase DDHD2; SAM; SAM; WWE and DDHD domain containing protein 1; SAMWD1; WWE and DDHD domain-containing protein 1

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