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The antibody against DDHD2 was raised in rabbit using the Recombinant Human Phospholipase DDHD2 protein (361-650AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DDHD2 was raised in rabbit using the Recombinant Human Phospholipase DDHD2 protein (361-650AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-25079A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DDHD2 |
| Form | Liquid | Species Reactivity | Human, Rat |
| Isotype | IgG | Storage Buffer | 0.02% sodium azideConstituents: PBS containing 50% glycerol |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Phospholipase DDHD2 protein (361-650AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O94830 |
Uniprot Id
O94830
Target Species
Human
Target Name
DDHD2
Target Full Name
Triacylglycerol hydrolase DDHD2
Target Function
Phospholipase that hydrolyzes preferentially phosphatidic acid, including 1,2-dioleoyl-sn-phosphatidic acid, and phosphatidylethanolamine. Specifically binds to phosphatidylinositol 3-phosphate (PI(3)P), phosphatidylinositol 4-phosphate (PI(4)P), phosphatidylinositol 5-phosphate (PI(5)P) and possibly phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2). May be involved in the maintenance of the endoplasmic reticulum and/or Golgi structures. May regulate the transport between Golgi apparatus and plasma membrane.
Target Involvement
Spastic paraplegia 54, autosomal recessive (SPG54)
Target Subcellular Location
Cytoplasm, cytosol. Endoplasmic reticulum-Golgi intermediate compartment. Golgi apparatus, cis-Golgi network. Note=Cycles between the Golgi apparatus and the cytosol. DDHD2 recruitment to the Golgi/endoplasmic reticulum-Golgi intermediate compartment (ERGIC) is regulated by the levels of phosphoinositides, including PI(4)P.
Target Protein Families
PA-PLA1 family
Target Tissue Specificity
Widely expressed (at protein level).
Target Synonyms
DDHD domain containing protein 2; DDHD domain-containing protein 2; Ddhd2; DDHD2_HUMAN; KIAA0725; mKIAA0725; Phospholipase DDHD2; SAM; SAM; WWE and DDHD domain containing protein 1; SAMWD1; WWE and DDHD domain-containing protein 1
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