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The antibody against DECR2 was raised in rabbit using the Synthesized peptide derived from internal of Human DECR2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against DECR2 was raised in rabbit using the Synthesized peptide derived from internal of Human DECR2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from LOVO cells, using DECR2 antibody.
| Cat.No | ADC-41053A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DECR2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human DECR2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NUI1 |
Uniprot Id
Q9NUI1
Target Species
Human
Target Name
DECR2
Target Full Name
Peroxisomal 2,4-dienoyl-CoA reductase [(3E)-enoyl-CoA-producing]
Target Function
Auxiliary enzyme of beta-oxidation. Participates in the degradation of unsaturated fatty enoyl-CoA esters having double bonds in both even- and odd-numbered positions in peroxisome. Catalyzes the NADP-dependent reduction of 2,4-dienoyl-CoA to yield trans-3-enoyl-CoA. Has activity towards short and medium chain 2,4-dienoyl-CoAs, but also towards 2,4,7,10,13,16,19-docosaheptaenoyl-CoA, suggesting that it does not constitute a rate limiting step in the peroxisomal degradation of docosahexaenoic acid.
Target Subcellular Location
Peroxisome.
Target Protein Families
Short-chain dehydrogenases/reductases (SDR) family, 2,4-dienoyl-CoA reductase subfamily
Target Synonyms
2 4 dienoyl CoA reductase 2; 2 4 dienoyl CoA reductase 2 peroxisomal; 2; 4-dienoyl-CoA reductase 2; 4-dienoyl-CoA reductase; DECR 2; Decr2; DECR2_HUMAN; EC 1.3.1.34; pDCR; Peroxisomal 2 4 dienoyl CoA reductase; Peroxisomal 2; SDR17C1; Short chain dehydrogenase/reductase family 17C member 1
Target Background
Enables 2, 4-dienoyl-CoA reductase (NADPH) activity and trans-2-enoyl-CoA reductase (NADPH) activity. Involved in unsaturated fatty acid biosynthetic process. Predicted to be located in peroxisome.
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