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The antibody against DEDD was raised in rabbit using the Recombinant Human Death effector domain-containing protein (1-318AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against DEDD was raised in rabbit using the Recombinant Human Death effector domain-containing protein (1-318AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$299.00
Immunohistochemistry of paraffin-embedded human prostate cancer using DEDD Antibody at dilution of 1:1002
| Cat.No | ADC-17553A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DEDD |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Death effector domain-containing protein (1-318AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75618 |
Uniprot Id
O75618
Target Species
Human
Target Name
DEDD
Target Full Name
Death effector domain-containing protein
Target Function
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro.
Target Subcellular Location
Cytoplasm. Nucleus, nucleolus.
Target Tissue Specificity
Widely expressed with highest levels in testis.
Target Research Area
Cell Biology
Target Synonyms
CASP8IP1; Death effector domain containing; Death effector domain containing protein; Death effector domain containing testicular molecule; Death effector domain-containing protein; Death effector domain-containing testicular molecule; DEDD 1; dedD; DEDD_HUMAN; DEDD1; DEDPro 1; DEDPro1; DEFT; FLDED 1; FLDED-1; FLDED1; KE 05; KE05; OTTHUMP00000031822
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