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The antibody against DGKG was raised in rabbit using the Recombinant Human Diacylglycerol kinase gamma protein (1-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
The antibody against DGKG was raised in rabbit using the Recombinant Human Diacylglycerol kinase gamma protein (1-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-22132A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DGKG |
| Target Synonyms | DGKG antibody; DAGK3Diacylglycerol kinase gamma antibody; DAG kinase gamma antibody; EC 2.7.1.107 antibody; Diglyceride kinase gamma antibody; DGK-gamma antibody | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Diacylglycerol kinase gamma protein (1-255AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P49619 |
Uniprot Id
P49619
Target Species
Human
Target Name
DGKG
Target Full Name
Diacylglycerol kinase gamma
Target Function
Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination.
Target Subcellular Location
Membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton.
Target Protein Families
Eukaryotic diacylglycerol kinase family
Target Tissue Specificity
Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma.
Target Research Area
Cell Biology
Target Synonyms
DGKG; DAGK3Diacylglycerol kinase gamma; DAG kinase gamma; EC 2.7.1.107; Diglyceride kinase gamma; DGK-gamma
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