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Rabbit anti-Human DGKG Polyclonal Antibody

The antibody against DGKG was raised in rabbit using the Recombinant Human Diacylglycerol kinase gamma protein (1-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

ADC-22132A

The antibody against DGKG was raised in rabbit using the Recombinant Human Diacylglycerol kinase gamma protein (1-255AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB.

$299.00

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Specifications


Cat.No ADC-22132A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDGKG
Target SynonymsDGKG antibody; DAGK3Diacylglycerol kinase gamma antibody; DAG kinase gamma antibody; EC 2.7.1.107 antibody; Diglyceride kinase gamma antibody; DGK-gamma antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human Diacylglycerol kinase gamma protein (1-255AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP49619
Background Information
  • Uniprot Id

    P49619

  • Target Species

    Human

  • Target Name

    DGKG

  • Target Full Name

    Diacylglycerol kinase gamma

  • Target Function

    Diacylglycerol kinase that converts diacylglycerol/DAG into phosphatidic acid/phosphatidate/PA and regulates the respective levels of these two bioactive lipids. Thereby, acts as a central switch between the signaling pathways activated by these second messengers with different cellular targets and opposite effects in numerous biological processes. Has no apparent specificity with regard to the acyl compositions of diacylglycerol. Specifically expressed in the cerebellum where it controls the level of diacylglycerol which in turn regulates the activity of protein kinase C gamma. Through protein kinase C gamma, indirectly regulates the dendritic development of Purkinje cells, cerebellar long term depression and ultimately cerebellar motor coordination.

  • Target Subcellular Location

    Membrane. Cytoplasm, cytosol. Cytoplasm, cytoskeleton.

  • Target Protein Families

    Eukaryotic diacylglycerol kinase family

  • Target Tissue Specificity

    Predominantly expressed in retina and in a much lesser extent in the brain. Other tissues contain extremely low levels of DGK-gamma.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    DGKG; DAGK3Diacylglycerol kinase gamma; DAG kinase gamma; EC 2.7.1.107; Diglyceride kinase gamma; DGK-gamma

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