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The antibody against DHODH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 116-395 of human DHODH (NP_001352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against DHODH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 116-395 of human DHODH (NP_001352.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-11789A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DHODH |
| Target Synonyms | URA1; POADS; DHOdehase; DHODH | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse heart, Mouse kidney, Rat heart, HepG2, HL-60, MCF7, Mouse spleen, Rat kidney, SW620 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 116-395 of human DHODH (NP_001352.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q02127 | Immunogen Sequence |
Uniprot Id
Q02127
Target Species
Human
Target Name
DHODH
Target Full Name
Dihydroorotate dehydrogenase (quinone), mitochondrial
Target Function
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Target Involvement
Postaxial acrofacial dysostosis (POADS)
Target Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Target Protein Families
Dihydroorotate dehydrogenase family, Type 2 subfamily
Target Research Area
Metabolism, Signal Transduction
Target Synonyms
DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1
Target Background
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
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