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The antibody against DHODH was raised in rabbit using the Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial protein (241-395AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DHODH was raised in rabbit using the Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial protein (241-395AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human breast cancer using DHODH Antibody at dilution of 1:100
| Cat.No | ADC-08606A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DHODH |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dihydroorotate dehydrogenase (quinone), mitochondrial protein (241-395AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q02127 |
Uniprot Id
Q02127
Target Species
Human
Target Name
DHODH
Target Full Name
Dihydroorotate dehydrogenase (quinone), mitochondrial
Target Function
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
Target Involvement
Postaxial acrofacial dysostosis (POADS)
Target Subcellular Location
Mitochondrion inner membrane; Single-pass membrane protein.
Target Protein Families
Dihydroorotate dehydrogenase family, Type 2 subfamily
Target Research Area
Metabolism, Signal Transduction
Target Synonyms
DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1
Target Background
The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.
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