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Rabbit anti-Human DHODH Polyclonal Antibody

The antibody against DHODH was raised in rabbit using the Human DHODH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-48761A

The antibody against DHODH was raised in rabbit using the Human DHODH as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-48761A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDHODH
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman DHODHTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ02127
Background Information
  • Uniprot Id

    Q02127

  • Target Species

    Human

  • Target Name

    DHODH

  • Target Full Name

    Dihydroorotate dehydrogenase (quinone), mitochondrial

  • Target Function

    Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.

  • Target Involvement

    Postaxial acrofacial dysostosis (POADS)

  • Target Subcellular Location

    Mitochondrion inner membrane; Single-pass membrane protein.

  • Target Protein Families

    Dihydroorotate dehydrogenase family, Type 2 subfamily

  • Target Research Area

    Metabolism, Signal Transduction

  • Target Synonyms

    DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1

  • Target Background

    The protein encoded by this gene catalyzes the fourth enzymatic step, the ubiquinone-mediated oxidation of dihydroorotate to orotate, in de novo pyrimidine biosynthesis. This protein is a mitochondrial protein located on the outer surface of the inner mitochondrial membrane.

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