Rabbit anti-Human DIAPH2 Polyclonal Antibody

The antibody against DIAPH2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DIAPH2 (NP_009293.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01334A

Number

Cat.No	ADA-01334A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	DIAPH2
Target Synonyms	DIA; POF; DIA2; DRF2; POF2; POF2A; DIAPH2	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, 293T, LO2, Mouse liver, NCI-H460, Rat liver, SKOV3, SW620	Application	ELISA, WB

Cat.No

ADA-01334A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

DIAPH2

Target Synonyms

DIA; POF; DIA2; DRF2; POF2; POF2A; DIAPH2

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, 293T, LO2, Mouse liver, NCI-H460, Rat liver, SKOV3, SW620

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DIAPH2 (NP_009293.1).	Target Species	Human
Immunogen Sequence	MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLN	Uniprot ID	O60879

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human DIAPH2 (NP_009293.1).

Target Species

Human

Immunogen Sequence

MEQPGAAASGAGGGSEEPGGGRSNKRSAGNRAANEEETKNKPKLNIQIKTLADDVRDRITSFRKSTVKKEKPLIQHPIDSQVAMSEFPAAQPLYDERSLNLSEKEVLDLFEKMMEDMNLN

Uniprot ID

O60879

Background Information

Uniprot Id

O60879
Target Species

Human
Target Name

DIAPH2
Target Full Name

Protein diaphanous homolog 2
Target Function

Could be involved in oogenesis. Involved in the regulation of endosome dynamics. Implicated in a novel signal transduction pathway, in which isoform 3 and CSK are sequentially activated by RHOD to regulate the motility of early endosomes through interactions with the actin cytoskeleton.
Target Involvement

Premature ovarian failure 2A (POF2A)
Target Subcellular Location

[Isoform 3]: Cytoplasm, cytosol. Early endosome. Note=Isoform 3 is cytosolic but when coexpressed with RHOD, the 2 proteins colocalize to early endosomes.
Target Protein Families

Formin homology family, Diaphanous subfamily
Target Tissue Specificity

Expressed in testis, ovary, small intestine, prostate, lung, liver, kidney and leukocytes.
Target Synonyms

Dia 2; DIA; Dia drome; Dia2; Diap 2; Diap2; DIAP2_HUMAN; DIAPH 2; Diaph2; Diaphanous 2; Diaphanous homolog 2 (Drosophila); Diaphanous homolog 2; Diaphanous related formin 2; Diaphanous-related formin-2; Diaphanous2; Diaphorase 2; Diaphorase2; DRF 2; DRF2; FLJ11167; OTTHUMP00000024270; OTTHUMP00000024271; OTTHUMP00000062171; POF 2; POF; POF2; Protein diaphanous homolog 2
Target Background

The product of this gene belongs to the diaphanous subfamily of the formin homology family of proteins. This gene may play a role in the development and normal function of the ovaries. Defects in this gene have been linked to premature ovarian failure 2. Alternatively spliced transcript variants encoding different isoforms have been identified.

Rabbit anti-Human DIAPH2 Polyclonal Antibody

Specifications

Immunogen Information

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