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The antibody against DIXDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DIXDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04978A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DIXDC1 |
| Target Synonyms | CCD1; DIXDC1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, MCF7 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q155Q3 | Immunogen Sequence |
Uniprot Id
Q155Q3
Target Species
Human
Target Name
DIXDC1
Target Full Name
Dixin
Target Function
Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.
Target Subcellular Location
Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm.; [Isoform 2]: Cytoplasm.
Target Protein Families
DIXDC1 family
Target Tissue Specificity
Ubiquitously expressed with higher expression in cardiac and skeletal muscles.
Target Synonyms
CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; Coiled coil DIX1 ; Coiled coil protein DIX1 ; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain containing protein 1; DIX domain-containing protein 1; DIXC1_HUMAN; DIXDC1; Dixin; KIAA1735
Target Background
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.
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