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Rabbit anti-Human DIXDC1 Polyclonal Antibody

The antibody against DIXDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-04978A

The antibody against DIXDC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-04978A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDIXDC1
Target SynonymsCCD1; DIXDC1FormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive Samples293T, MCF7ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 173-472 of human DIXDC1 (NP_219493.1).Target SpeciesHuman
Uniprot IDQ155Q3Immunogen Sequence
Background Information
  • Uniprot Id

    Q155Q3

  • Target Species

    Human

  • Target Name

    DIXDC1

  • Target Full Name

    Dixin

  • Target Function

    Positive effector of the Wnt signaling pathway; activates WNT3A signaling via DVL2. Regulates JNK activation by AXIN1 and DVL2.

  • Target Subcellular Location

    Cell junction, focal adhesion. Cytoplasm, cytoskeleton, stress fiber. Cytoplasm.; [Isoform 2]: Cytoplasm.

  • Target Protein Families

    DIXDC1 family

  • Target Tissue Specificity

    Ubiquitously expressed with higher expression in cardiac and skeletal muscles.

  • Target Synonyms

    CCD1; Ccd1Aalpha1L; Ccd1Abeta1L; Ccd1BalphaL; Ccd1BbetaL; Ccd1CL; Coiled coil DIX1 ; Coiled coil protein DIX1 ; Coiled-coil protein DIX1; Coiled-coil-DIX1; DIX domain containing 1; DIX domain containing protein 1; DIX domain-containing protein 1; DIXC1_HUMAN; DIXDC1; Dixin; KIAA1735

  • Target Background

    The protein encoded by this gene is a positive regulator of the Wnt signaling pathway. The encoded protein is found associated with gamma tubulin at the centrosome. Alternative splicing results in multiple transcript variants encoding different isoforms.

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