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The antibody against DKKL1 was raised in rabbit using the Recombinant Human Dickkopf-like protein 1 protein (31-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against DKKL1 was raised in rabbit using the Recombinant Human Dickkopf-like protein 1 protein (31-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human testis tissue using DKKL1 Antibody at dilution of 1:100
| Cat.No | ADC-17707A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DKKL1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dickkopf-like protein 1 protein (31-242AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UK85 |
Uniprot Id
Q9UK85
Target Species
Human
Target Name
DKKL1
Target Full Name
Dickkopf-like protein 1
Target Function
Involved in fertilization by facilitating sperm penetration of the zona pellucida. May promote spermatocyte apoptosis, thereby limiting sperm production. In adults, may reduce testosterone synthesis in Leydig cells. Is not essential either for development or fertility.
Target Subcellular Location
Secreted. Cytoplasmic vesicle, secretory vesicle, acrosome.
Target Tissue Specificity
More highly expressed in adult testis than in fetal testis. Exclusively expressed in the testis (at protein level). Intense expression in stages II, III and IV of spermatogenesis, whereas expression is lower in stage I.
Target Synonyms
Cancer/testis antigen 34; CT34; dickkopf like 1; Dickkopf-like protein 1; DKKL1; DKKL1_HUMAN; Protein soggy-1; SGY; SGY-1; SGY1; soggy 1
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