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The antibody against DLG3 was raised in rabbit using the Human DLG3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against DLG3 was raised in rabbit using the Human DLG3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-53570A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DLG3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human DLG3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q92796 |
Uniprot Id
Q92796
Target Species
Human
Target Name
DLG3
Target Full Name
Disks large homolog 3
Target Function
Required for learning most likely through its role in synaptic plasticity following NMDA receptor signaling.
Target Involvement
Mental retardation, X-linked 90 (MRX90)
Target Protein Families
MAGUK family
Target Synonyms
bA291O7.3; bA291O7.3 discs large Drosophila homolog 3 neuroendocrine dlg; Discs large Drosophila homolog 3; Discs large homolog 3 neuroendocrine dlg Drosophila; Discs large homolog 3; Discs large homolog 3 Drosophila; Discs, large homolog 3 (Drosophila); Disks large homolog 3; DLG 3; Dlg3; DLG3_HUMAN; KIAA1232; mKIAA1232; MRX 90; MRX; MRX90; NE Dlg ; NEDLG; Neuroendocrine dlg ; Neuroendocrine-DLG; OTTHUMP00000023475; OTTHUMP00000023476; OTTHUMP00000023477; SAP 102; SAP-102; SAP102; Synapse associated protein 102; Synapse-associated protein 102; XLMR
Target Background
This gene encodes a member of the membrane-associated guanylate kinase protein family. The encoded protein may play a role in clustering of NMDA receptors at excitatory synapses. It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein. Mutations in this gene have been associated with X-linked cognitive disability. Alternatively spliced transcript variants have been described.
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