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The antibody against DLK1 was raised in rabbit using the Peptide sequence around aa.375~379(S-K-E-A-G) derived from Human DLK1. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
The antibody against DLK1 was raised in rabbit using the Peptide sequence around aa.375~379(S-K-E-A-G) derived from Human DLK1. as the immunogen. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. This antibody has been validated on ELISA, WB.
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Western blot analysis of extract from HepG2 and PC12 cells using DLK1 Antibody
| Cat.No | ADC-43179A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DLK1 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Peptide sequence around aa.375~379(S-K-E-A-G) derived from Human DLK1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P80370 |
Uniprot Id
P80370
Target Species
Human
Target Name
DLK1
Target Full Name
Protein delta homolog 1
Target Function
May have a role in neuroendocrine differentiation.
Target Subcellular Location
Membrane; Single-pass type I membrane protein. Cytoplasm.
Target Tissue Specificity
Found within the stromal cells in close contact to the vascular structure of placental villi, yolk sac, fetal liver, adrenal cortex and pancreas and in the beta cells of the islets of Langerhans in the adult pancreas. Found also in some forms of neuroendo
Target Research Area
Neuroscience
Target Synonyms
Adipocyte differentiation inhibitor protein; Brevideltin; Delta like 1 homolog; Delta like homolog; Delta like protein; Delta1; DLK 1; DLK; DLK-1; DLK1; DLK1_HUMAN; FA 1; FA1; Fetal antigen 1; pG2; Preadipocyte factor 1; Pref 1; Pref; Pref1; Protein delta homolog 1; Secredeltin; ZOG
Target Background
This gene encodes a transmembrane protein that contains multiple epidermal growth factor repeats that functions as a regulator of cell growth. The encoded protein is involved in the differentiation of several cell types including adipocytes. This gene is located in a region of chromosome 14 frequently showing unparental disomy, and is imprinted and expressed from the paternal allele. A single nucleotide variant in this gene is associated with child and adolescent obesity and shows polar overdominance, where heterozygotes carrying an active paternal allele express the phenotype, while mutant homozygotes are normal.
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