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The antibody against DMC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DMC1 (NP_008999.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DMC1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DMC1 (NP_008999.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-12272A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DMC1 |
| Target Synonyms | DMC1H; LIM15; dJ199H16.1; DMC1 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse testis, Rat testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DMC1 (NP_008999.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q14565 | Immunogen Sequence |
Uniprot Id
Q14565
Target Species
Human
Target Name
DMC1
Target Full Name
Meiotic recombination protein DMC1/LIM15 homolog
Target Function
Participates in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks.
Target Subcellular Location
Nucleus. Chromosome.
Target Protein Families
RecA family, DMC1 subfamily
Target Synonyms
Disrupted meiotic cDNA 1 homolog ; Disrupted meiotic cDNA 1; yeast; homolog of; dJ199H16.1; DMC 1; DMC1; DMC1 dosage suppressor of mck1 homolog; DMC1 dosage suppressor of mck1 homolog meiosis specific homologous recombination (yeast); DMC1 homologue ; DMC1_HUMAN; DMC1H; DNA meiotic recombinase 1; HsLim15; LIM15; Meiotic recombination protein DMC1/LIM15 homolog; MGC150472; MGC150473
Target Background
This gene encodes a member of the superfamily of recombinases (also called DNA strand-exchange proteins). Recombinases are important for repairing double-strand DNA breaks during mitosis and meiosis. This protein, which is evolutionarily conserved, is reported to be essential for meiotic homologous recombination and may thus play an important role in generating diversity of genetic information. Alternative splicing results in multiple transcript variants.
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