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The antibody against DNAAF4 was raised in rabbit using the Recombinant Human Dynein assembly factor 4, axonemal protein (109-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DNAAF4 was raised in rabbit using the Recombinant Human Dynein assembly factor 4, axonemal protein (109-295AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using DNAAF4 Antibody at dilution of 1:1002
| Cat.No | ADC-13711A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DNAAF4 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Dynein assembly factor 4, axonemal protein (109-295AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8WXU2 |
Uniprot Id
Q8WXU2
Target Species
Human
Target Name
DNAAF4
Target Full Name
Dynein axonemal assembly factor 4
Target Function
Axonemal dynein assembly factor required for ciliary motility. Involved in neuronal migration during development of the cerebral neocortex. May regulate the stability and proteasomal degradation of the estrogen receptors that play an important role in neuronal differentiation, survival and plasticity.
Target Involvement
Dyslexia 1 (DYX1); Ciliary dyskinesia, primary, 25 (CILD25)
Target Subcellular Location
Nucleus. Cytoplasm. Dynein axonemal particle. Cell projection, neuron projection.
Target Tissue Specificity
Expressed in several tissues, including brain, lung, kidney and testis. In brain localizes to a fraction of cortical neurons and white matter glial cells.
Target Synonyms
Dyslexia susceptibility 1 candidate 1; Dyslexia susceptibility 1 candidate gene 1 protein; DYX1; DYX1C1; DYXC1; DYXC1_HUMAN; EKN1; FLJ37882; MGC70618; RD
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