Rabbit anti-Human DNAJC5 Polyclonal Antibody

The antibody against DNAJC5 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DNAJC5 (NP_079495.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01594A

Number

Cat.No	ADA-01594A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	DNAJC5
Target Synonyms	CSP; NCL; CLN4; CLN4B; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; DNAJC5	Form	Liquid
Species Reactivity	Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Rat brain, Mouse brain, Mouse liver	Application	ELISA, WB

Cat.No

ADA-01594A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

DNAJC5

Target Synonyms

CSP; NCL; CLN4; CLN4B; DNAJC5A; mir-941-2; mir-941-3; mir-941-4; mir-941-5; DNAJC5

Form

Liquid

Species Reactivity

Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Rat brain, Mouse brain, Mouse liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DNAJC5 (NP_079495.1).	Target Species	Human
Immunogen Sequence	MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN	Uniprot ID	Q9H3Z4

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-198 of human DNAJC5 (NP_079495.1).

Target Species

Human

Immunogen Sequence

MADQRQRSLSTSGESLYHVLGLDKNATSDDIKKSYRKLALKYHPDKNPDNPEAADKFKEINNAHAILTDATKRNIYDKYGSLGLYVAEQFGEENVNTYFVLSSWWAKALFVFCGLLTCCYCCCCLCCCFNCCCGKCKPKAPEGEETEFYVSPEDLEAQLQSDEREATDTPIVIQPASATETTQLTADSHPSYHTDGFN

Uniprot ID

Q9H3Z4

Background Information

Uniprot Id

Q9H3Z4
Target Species

Human
Target Name

DNAJC5
Target Full Name

DnaJ homolog subfamily C member 5
Target Function

Acts as a general chaperone in regulated exocytosis. Acts as a co-chaperone for the SNARE protein SNAP-25. Involved in the calcium-mediated control of a late stage of exocytosis. May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.
Target Involvement

Ceroid lipofuscinosis, neuronal, 4B (CLN4B)
Target Subcellular Location

Cytoplasm, cytosol. Membrane; Lipid-anchor. Cytoplasmic vesicle, secretory vesicle, chromaffin granule membrane. Melanosome. Cell membrane.
Target Tissue Specificity

Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.
Target Research Area

Neuroscience
Target Synonyms

CLN 4; CLN4; CLN4B; CSP; cysteine string protein alpha; Cysteine string protein; DJC5; DnaJ (Hsp40) homolog subfamily C member 5; DnaJ homolog subfamily C member 5; DNAJC 5; Dnajc5; DNAJC5A; DNJC5_HUMAN; NCL
Target Background

This gene is a member of the J protein family. J proteins function in many cellular processes by regulating the ATPase activity of 70 kDa heat shock proteins. The encoded protein plays a role in membrane trafficking and protein folding, and has been shown to have anti-neurodegenerative properties. The encoded protein is known to play a role in cystic fibrosis and Huntington's disease. A pseudogene of this gene is located on the short arm of chromosome 8.

Rabbit anti-Human DNAJC5 Polyclonal Antibody

Specifications

Immunogen Information

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