Rabbit anti-Human DNALI1 Polyclonal Antibody

Uniprot Id

O14645

Target Species

Human

Target Name

DNALI1

Target Full Name

Axonemal dynein light intermediate polypeptide 1

Target Function

May play a dynamic role in flagellar motility.

Target Subcellular Location

Cell projection, cilium. Cell projection, cilium, flagellum. Dynein axonemal particle.

Target Protein Families

Inner dynein arm light chain family

Target Tissue Specificity

Expressed in many tissues. A smaller 0.9 kb and a larger 2.5 kb transcripts were detected at the highest level in the testis, at medium levels in the prostate, heart, liver, lung and pancreas, at low levels in the ovary, skeletal muscle and small intestin

Target Synonyms

axonemal; Axonemal dynein light chain (hp28); Axonemal dynein light chain; Axonemal dynein light intermediate polypeptide 1; dJ423B22.5; DNALI 1; DNALI1; Dynein axonemal light intermediate chain 1; Dynein axonemal light intermediate polypeptide 1; hp28; IDLC_HUMAN; Inner dynein arm homolog of clamydomonas; Inner dynein arm light chain; Inner dynein arm light chain axonemal; P28

Target Background

This gene is the human homolog of the Chlamydomonas inner dynein arm gene, p28. The precise function of this gene is not known, however, it is a potential candidate for immotile cilia syndrome (ICS). Ultrastructural defects of the inner dynein arms are seen in patients with ICS. Immotile mutant strains of Chlamydomonas, a biflagellated algae, exhibit similar defects.