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The antibody against DOC2B was raised in rabbit using the Human DOC2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
The antibody against DOC2B was raised in rabbit using the Human DOC2B as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IF.
$600.00
| Cat.No | ADC-48723A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOC2B |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, WB | Storage | Upon receipt |
| Immunogen Description | Human DOC2B | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14184 |
Uniprot Id
Q14184
Target Species
Human
Target Name
DOC2B
Target Full Name
Double C2-like domain-containing protein beta
Target Function
Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
Target Subcellular Location
Cytoplasm. Cytoplasmic granule. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity
Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level).
Target Synonyms
Doc2 beta; Doc2-beta; Doc2b; DOC2B_HUMAN; DOC2BL; Double C2 like domain containing protein beta; Double C2 like domains beta; Double C2 like domains beta like; Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2
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