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The antibody against DOC2B was raised in rabbit using the Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
The antibody against DOC2B was raised in rabbit using the Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA) as the immunogen. This antibody exists as a biotin conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA.
$299.00
| Cat.No | ADC-13795A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOC2B |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Biotin conjugated |
| Application | ELISA | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Double C2-like domain-containing protein beta protein (7-180AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14184 |
Uniprot Id
Q14184
Target Species
Human
Target Name
DOC2B
Target Full Name
Double C2-like domain-containing protein beta
Target Function
Calcium sensor which positively regulates SNARE-dependent fusion of vesicles with membranes. Binds phospholipids in a calcium-dependent manner and may act at the priming stage of fusion by modifying membrane curvature to stimulate fusion. Involved in calcium-triggered exocytosis in chromaffin cells and calcium-dependent spontaneous release of neurotransmitter in absence of action potentials in neuronal cells. Involved both in glucose-stimulated insulin secretion in pancreatic cells and insulin-dependent GLUT4 transport to the plasma membrane in adipocytes.
Target Subcellular Location
Cytoplasm. Cytoplasmic granule. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity
Widely expressed with highest levels in brain and kidney. Expressed in pancreatic islet cells (at protein level).
Target Synonyms
Doc2 beta; Doc2-beta; Doc2b; DOC2B_HUMAN; DOC2BL; Double C2 like domain containing protein beta; Double C2 like domains beta; Double C2 like domains beta like; Double C2-like domain-containing protein beta; OTTMUSP00000006522; RP23 78H4.2
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