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The antibody against DOK7 was raised in rabbit using the Recombinant Human Protein Dok-7 protein (416-504AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
The antibody against DOK7 was raised in rabbit using the Recombinant Human Protein Dok-7 protein (416-504AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.
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| Cat.No | ADC-07265A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DOK7 |
| Target Synonyms | Docking protein 7 antibody; DOK 7 antibody; DOK7 antibody; DOK7_HUMAN antibody; Downstream of tyrosine kinase 7 antibody; Protein Dok-7 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | FITC conjugated | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Protein Dok-7 protein (416-504AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q18PE1 |
Uniprot Id
Q18PE1
Target Species
Human
Target Name
DOK7
Target Full Name
Protein Dok-7
Target Function
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
Target Involvement
Myasthenic syndrome, congenital, 10 (CMS10)
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Cell junction, synapse.
Target Tissue Specificity
Preferentially expressed in skeletal muscle and heart. Present in thigh muscle, diaphragm and heart but not in the liver or spleen (at protein level).
Target Synonyms
Docking protein 7; DOK 7; DOK7; DOK7_HUMAN; Downstream of tyrosine kinase 7; Protein Dok-7
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