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The antibody against DRAM2 was raised in rabbit using the Recombinant Human DNA damage-regulated autophagy modulator protein 2 protein (182-266AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
The antibody against DRAM2 was raised in rabbit using the Recombinant Human DNA damage-regulated autophagy modulator protein 2 protein (182-266AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human heart tissue using DRAM2 Antibody at dilution of 1:100
Immunofluorescent analysis of MCF-7 cells using DRAM2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-16992A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DRAM2 |
| Target Synonyms | DRAM2; TMEM77; PSEC0031; UNQ154/PRO180; DNA damage-regulated autophagy modulator protein 2; Transmembrane protein 77 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human DNA damage-regulated autophagy modulator protein 2 protein (182-266AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6UX65 |
Uniprot Id
Q6UX65
Target Species
Human
Target Name
DRAM2
Target Full Name
DNA damage-regulated autophagy modulator protein 2
Target Function
Plays a role in the initiation of autophagy. In the retina, might be involved in the process of photoreceptor cells renewal and recycling to preserve visual function. Induces apoptotic cell death when coexpressed with DRAM1.
Target Subcellular Location
Lysosome membrane; Multi-pass membrane protein. Photoreceptor inner segment. Apical cell membrane.
Target Protein Families
DRAM/TMEM150 family
Target Tissue Specificity
Expression is down-regulated in ovarian tumors (at protein level). Widely expressed with highest levels in placenta and heart. Expressed in the retina. Not detected in brain or thymus.
Target Synonyms
DRAM2; TMEM77; PSEC0031; UNQ154/PRO180; DNA damage-regulated autophagy modulator protein 2; Transmembrane protein 77
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