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Rabbit anti-Human DRD1 Polyclonal Antibody

The antibody against DRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11268A

The antibody against DRD1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-11268A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDRD1
Target SynonymsDADR; DRD1A; DRD1FormLiquid
Species ReactivityRatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesRat brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 338-446 of human DRD1 (NP_000785.1).Target SpeciesHuman
Immunogen SequenceRKAFSTLLGCYRLCPATNNAIETVSINNNGAAMFSSHHEPRGSISKECNLVYLIPHAVGSSEDLKKEEAAGIARPLEKLSPALSVILDYDTDVSLEKIQPITQNGQHPTUniprot IDP21728
Background Information
  • Uniprot Id

    P21728

  • Target Species

    Human

  • Target Name

    DRD1

  • Target Full Name

    D(1A) dopamine receptor

  • Target Function

    Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.

  • Target Subcellular Location

    Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine.

  • Target Protein Families

    G-protein coupled receptor 1 family

  • Target Tissue Specificity

    Detected in caudate, nucleus accumbens and in the olfactory tubercle.

  • Target Research Area

    Neuroscience

  • Target Synonyms

    DRD1; D(1A dopamine receptor; Dopamine D1 receptor

  • Target Background

    This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.

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