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The antibody against DRD1 was raised in rabbit using the Recombinant Human D(1A) dopamine receptor protein (338-446AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against DRD1 was raised in rabbit using the Recombinant Human D(1A) dopamine receptor protein (338-446AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry analysis of human lung cancer using DRD1 Antibody at dilution of 1:1002
| Cat.No | ADC-14044A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DRD1 |
| Target Synonyms | DRD1; D(1A dopamine receptor; Dopamine D1 receptor | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human D(1A) dopamine receptor protein (338-446AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P21728 |
Uniprot Id
P21728
Target Species
Human
Target Name
DRD1
Target Full Name
D(1A) dopamine receptor
Target Function
Dopamine receptor whose activity is mediated by G proteins which activate adenylyl cyclase.
Target Subcellular Location
Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, dendritic spine.
Target Protein Families
G-protein coupled receptor 1 family
Target Tissue Specificity
Detected in caudate, nucleus accumbens and in the olfactory tubercle.
Target Research Area
Neuroscience
Target Synonyms
DRD1; D(1A dopamine receptor; Dopamine D1 receptor
Target Background
This gene encodes the D1 subtype of the dopamine receptor. The D1 subtype is the most abundant dopamine receptor in the central nervous system. This G-protein coupled receptor stimulates adenylyl cyclase and activates cyclic AMP-dependent protein kinases. D1 receptors regulate neuronal growth and development, mediate some behavioral responses, and modulate dopamine receptor D2-mediated events. Alternate transcription initiation sites result in two transcript variants of this gene.
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