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The antibody against DRP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against DRP2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-04920A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DRP2 |
| Target Synonyms | DRP-2; DRP2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse brain | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human DRP2 (NP_001930.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q13474 | Immunogen Sequence |
Uniprot Id
Q13474
Target Species
Human
Target Name
DRP2
Target Full Name
Dystrophin-related protein 2
Target Function
Required for normal myelination and for normal organization of the cytoplasm and the formation of Cajal bands in myelinating Schwann cells. Required for normal PRX location at appositions between the abaxonal surface of the myelin sheath and the Schwann cell plasma membrane. Possibly involved in membrane-cytoskeleton interactions of the central nervous system.
Target Subcellular Location
Cell junction, synapse, postsynaptic density. Cell projection, dendrite. Perikaryon. Cell membrane; Peripheral membrane protein.
Target Tissue Specificity
Detected in fetal brain.
Target Synonyms
DRP-2; Drp2; DRP2_HUMAN; Dystrophin-related protein 2
Target Background
Members of the dystrophin family of proteins perform a critical role in the maintenance of membrane-associated complexes at points of intercellular contact in vertebrate cells. The protein encoded by this gene is predicted to resemble certain short C-terminal isoforms of dystrophin and dystrophin-related protein 1 (DRP1 or utrophin). DRP2 is expressed principally in the brain and spinal cord. Two transcript variants encoding different isoforms have been found for this gene.
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