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The antibody against DTD1 was raised in rabbit using the Human DTD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against DTD1 was raised in rabbit using the Human DTD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$600.00
| Cat.No | ADC-45995A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DTD1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Human DTD1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8TEA8 |
Uniprot Id
Q8TEA8
Target Species
Human
Target Name
DTD1
Target Full Name
D-aminoacyl-tRNA deacylase 1
Target Function
Possible ATPase involved in DNA replication, may facilitate loading of CDC45 onto pre-replication complexes.; An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.
Target Subcellular Location
Nucleus. Cytoplasm. Note=Associated with chromatin at some replication origins containing functional DNA-unwinding elements (PubMed:20065034).
Target Protein Families
DTD family
Target Tissue Specificity
Expressed in many adult and fetal tissues. Highest levels in testis, ovary, spleen and in adult and fetal brain.
Target Synonyms
bA379J5.3; bA555E18.1; C20orf88; D tyrosyl tRNA deacylase 1 homolog; D-tyrosyl-tRNA(Tyr) deacylase 1; DNA unwinding element binding protein; DTD1; DTD1_HUMAN; DUE B; DUEB; HARS2; Histidyl tRNA synthetase 2; Histidyl-tRNA synthase-related; MGC119131; MGC41905; pqn 68
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