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Rabbit anti-Human DUSP22 Polyclonal Antibody

The antibody against DUSP22 was raised in rabbit using the Human DUSP22 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-48701A

The antibody against DUSP22 was raised in rabbit using the Human DUSP22 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-48701A ClonalityPolyclonal
Host SpeciesRabbitTarget NameDUSP22
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman DUSP22Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9NRW4
Background Information
  • Uniprot Id

    Q9NRW4

  • Target Species

    Human

  • Target Name

    DUSP22

  • Target Full Name

    Dual specificity protein phosphatase 22

  • Target Function

    Activates the Jnk signaling pathway.

  • Target Subcellular Location

    Cytoplasm.

  • Target Protein Families

    Protein-tyrosine phosphatase family, Non-receptor class dual specificity subfamily

  • Target Tissue Specificity

    Ubiquitous. Highest expression seen in heart, placenta, lung, liver, kidney and pancreas.

  • Target Research Area

    Cell Biology

  • Target Synonyms

    Dual specificity protein phosphatase 22; DUS22_HUMAN; Dusp22; JNK stimulatory phosphatase 1; JNK-stimulatory phosphatase-1; JSP 1; JSP-1; JSP1; LMW DSP2; LMW-DSP2; Low molecular weight dual specificity phosphatase 2; MAP kinase phosphatase x; Mitogen activated protein kinase phosphatase x; Mitogen-activated protein kinase phosphatase x; MKP-x; MKPX

  • Target Background

    Enables non-membrane spanning protein tyrosine phosphatase activity and protein tyrosine kinase binding activity. Involved in several processes, including cellular response to epidermal growth factor stimulus; negative regulation of focal adhesion assembly; and negative regulation of non-membrane spanning protein tyrosine kinase activity. Acts upstream of or within negative regulation of transcription by RNA polymerase II. Located in plasma membrane. Part of cytoplasm; filamentous actin; and leading edge of lamellipodium.

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