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The antibody against DVL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 580-650 of human DVL3 (NP_004414.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against DVL3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 580-650 of human DVL3 (NP_004414.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-09784A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | DVL3 |
| Target Synonyms | DRS3; DVL3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | C6, NIH/3T3, Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 580-650 of human DVL3 (NP_004414.3). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | RSGSDRRKEKDPKAGDSKSGGSGSESDHTTRSSLRGPRERAPSERSGPAASEHSHRSHHSLASSLRSHHTH | Uniprot ID | Q92997 |
Uniprot Id
Q92997
Target Species
Human
Target Name
DVL3
Target Full Name
Segment polarity protein dishevelled homolog DVL-3
Target Function
Involved in the signal transduction pathway mediated by multiple Wnt genes.
Target Involvement
Robinow syndrome, autosomal dominant 3 (DRS3)
Target Subcellular Location
Cytoplasm.
Target Protein Families
DSH family
Target Research Area
Cardiovascular
Target Synonyms
Dishevelled 3 (homologous to Drosophila dsh) ; Dishevelled 3; Dishevelled 3; dsh homolog (Drosophila); Dishevelled; dsh homolog 3 (Drosophila); Dishevelled-3; DSH homolog 3; dvl3; DVL3_HUMAN; KIAA0208; OTTHUMP00000210777; OTTHUMP00000210778; Segment polarity protein dishevelled homolog DVL 3; Segment polarity protein dishevelled homolog DVL-3
Target Background
This gene is a member of a multi-gene family which shares strong similarity with the Drosophila dishevelled gene, dsh. The Drosophila dishevelled gene encodes a cytoplasmic phosphoprotein that regulates cell proliferation.
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