Rabbit anti-Human ECI1 Polyclonal Antibody

Uniprot Id

P42126

Target Species

Human

Target Name

ECI1

Target Full Name

Enoyl-CoA delta isomerase 1, mitochondrial

Target Function

Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species.

Target Subcellular Location

Mitochondrion matrix.

Target Protein Families

Enoyl-CoA hydratase/isomerase family

Target Tissue Specificity

Expressed in liver (at protein level).

Target Synonyms

2-trans-enoyl-CoA isomerase; 3; 3,2 trans enoyl Coenzyme A isomerase ; 3,2 trans-enoyl-CoA isomerase; 3,2-trans-enoyl-CoA isomerase; mitochondrial; Acetylene allene isomerase; D2-enoyl-CoA isomerase; D3; D3,D2 enoyl CoA isomerase ; DCI; DCI protein ; delta(2)-enoyl-CoA isomerase; Delta(3); Delta(3),Delta(2) enoyl CoA isomerase ; Delta3; delta2 enoyl CoA isomerase; Dodecenoyl CoA delta Isomerase; Dodecenoyl CoA isomerase; Dodecenoyl Coenzyme A delta isomerase ; Dodecenoyl Coenzyme A delta isomerase (3,2 trans enoyl Coenzyme A isomerase); Dodecenoyl Coenzyme A delta isomerase 3,2 trans enoyl Coenzyme A isomerase; isoform CRA a; Dodecenoyl-CoA isomerase; ECI1; ECI1_HUMAN; Enoyl-CoA delta isomerase 1; enoyl-CoA delta isomerase 1; mitochondrial; mitochondrial

Target Background

This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.