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The antibody against ECI2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human DRS-1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against ECI2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human DRS-1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
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Western Blot analysis of 293 cells using DRS-1 Polyclonal Antibody
Western Blot analysis of K562 cells using DRS-1 Polyclonal Antibody2
| Cat.No | ADC-38805A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ECI2 |
| Target Synonyms | 2-trans-enoyl-CoA isomerase antibody; Peroxisomal D3 D2 enoyl CoA isomerase antibody; Renal carcinoma antigen NY REN 1 antibody; Renal carcinoma antigen NY-REN-1 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human DRS-1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75521 |
Uniprot Id
O75521
Target Species
Human
Target Name
ECI2
Target Full Name
Enoyl-CoA delta isomerase 2
Target Function
Able to isomerize both 3-cis and 3-trans double bonds into the 2-trans form in a range of enoyl-CoA species. Has a preference for 3-trans substrates.
Target Subcellular Location
[Isoform 1]: Mitochondrion.; [Isoform 2]: Peroxisome matrix.
Target Protein Families
Enoyl-CoA hydratase/isomerase family
Target Tissue Specificity
Abundant in heart, skeletal muscle and liver. Expressed in CD34(+) T-cells and CD34(+) bone marrow cells.
Target Synonyms
2-trans-enoyl-CoA isomerase; ACBD2 ; acyl Coenzyme A binding domain containing 2 ; D2-enoyl-CoA isomerase; D3; D3 D2 enoyl CoA isomerase; DBI related protein 1 ; DBI-related protein 1; delta(2)-enoyl-CoA isomerase; Delta(3); Delta(3) delta(2) enoyl CoA isomerase; Diazepam-binding inhibitor-related protein 1; Dodecenoyl CoA isomerase; Dodecenoyl-CoA isomerase; DRS 1 ; DRS-1; DRS1 ; Eci2; ECI2_HUMAN; Enoyl-CoA delta isomerase 2; HCA88 ; Hepatocellular carcinoma associated antigen 88; Hepatocellular carcinoma-associated antigen 88; mitochondrial; pECI; Peroxisomal 3; Peroxisomal 3,2-trans-enoyl-CoA isomerase; Peroxisomal D3 D2 enoyl CoA isomerase; Renal carcinoma antigen NY REN 1 ; Renal carcinoma antigen NY-REN-1
Target Background
This gene encodes a member of the hydratase/isomerase superfamily. The protein encoded is a key mitochondrial enzyme involved in beta-oxidation of unsaturated fatty acids. It catalyzes the transformation of 3-cis and 3-trans-enoyl-CoA esters arising during the stepwise degradation of cis-, mono-, and polyunsaturated fatty acids to the 2-trans-enoyl-CoA intermediates. Alternatively spliced transcript variants have been described.
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