Rabbit anti-Human ECSIT Polyclonal Antibody

The antibody against ECSIT was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 50-296 of human ECSIT (NP_001135936.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.

ADA-12091A

Number

Cat.No	ADA-12091A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ECSIT
Target Synonyms	SITPEC; ECSIT	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	HepG2	Application	ELISA, WB, IF/ICC

Cat.No

ADA-12091A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ECSIT

Target Synonyms

SITPEC; ECSIT

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

HepG2

Application

ELISA, WB, IF/ICC

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 50-296 of human ECSIT (NP_001135936.1).	Target Species	Human
Uniprot ID	Q9BQ95	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 50-296 of human ECSIT (NP_001135936.1).

Target Species

Human

Uniprot ID

Q9BQ95

Immunogen Sequence

Background Information

Uniprot Id

Q9BQ95
Target Species

Human
Target Name

ECSIT
Target Full Name

Evolutionarily conserved signaling intermediate in Toll pathway, mitochondrial
Target Function

Adapter protein of the Toll-like and IL-1 receptor signaling pathway that is involved in the activation of NF-kappa-B via MAP3K1. Promotes proteolytic activation of MAP3K1. Involved in the BMP signaling pathway. Required for normal embryonic development.; Required for efficient assembly of mitochondrial NADH:ubiquinone oxidoreductase.
Target Subcellular Location

Cytoplasm. Nucleus. Mitochondrion.
Target Protein Families

ECSIT family
Target Synonyms

Ecsit; ECSIT homolog; ECSIT protein; ECSIT_HUMAN; Evolutionarily conserved signaling intermediate in Toll pathway; mitochondrial; Evolutionarily conserved signaling intermediate in Toll pathways; Likely ortholog of mouse signaling intermediate in Toll pathway evolutionarily conserved; Protein SITPEC; Signaling intermediate in Toll pathway evolutionarily conserved; SITPEC; SITPEC protein
Target Background

Predicted to enable DNA-binding transcription factor activity and chromatin binding activity. Involved in regulation of oxidoreductase activity and regulation of protein complex stability. Located in cytosol; mitochondrion; and nucleoplasm.

Rabbit anti-Human ECSIT Polyclonal Antibody

Specifications

Immunogen Information

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