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The antibody against EDNRA was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ETAR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against EDNRA was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human ETAR. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of COS7 cells using ETAR Polyclonal Antibody
| Cat.No | ADC-38707A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EDNRA |
| Target Synonyms | EDNRA; ETA; ETRA; Endothelin-1 receptor; Endothelin receptor type A; ET-A; ETA-R; hET-AR | Form | Liquid |
| Species Reactivity | Human, Mouse, Monkey | Isotype | IgG |
| Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human ETAR. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P25101 |
Uniprot Id
P25101
Target Species
Human
Target Name
EDNRA
Target Full Name
Endothelin-1 receptor
Target Function
Receptor for endothelin-1. Mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of binding affinities for ET-A is: ET1 > ET2 >> ET3.
Target Involvement
Mandibulofacial dysostosis with alopecia (MFDA)
Target Subcellular Location
Cell membrane; Multi-pass membrane protein.
Target Protein Families
G-protein coupled receptor 1 family, Endothelin receptor subfamily, EDNRA sub-subfamily
Target Tissue Specificity
Isoform 1, isoform 3 and isoform 4 are expressed in a variety of tissues, with highest levels in the aorta and cerebellum, followed by lung, atrium and cerebral cortex, lower levels in the placenta, kidney, adrenal gland, duodenum, colon, ventricle and li
Target Research Area
Signal Transduction
Target Synonyms
EDNRA; ETA; ETRA; Endothelin-1 receptor; Endothelin receptor type A; ET-A; ETA-R; hET-AR
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