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The antibody against EFTUD2 was raised in rabbit using the Recombinant Human 116 kDa U5 small nuclear ribonucleoprotein component protein (1-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against EFTUD2 was raised in rabbit using the Recombinant Human 116 kDa U5 small nuclear ribonucleoprotein component protein (1-205AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skin tissue using EFTUD2 Antibody at dilution of 1:100
| Cat.No | ADC-44897A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EFTUD2 |
| Target Synonyms | 116 kD antibody; U5 snRNP specific protein, 116 kDa antibody; U5 snRNP-specific protein antibody; U5-116 kDa antibody; U5-116KD antibody; U5S1_HUMAN antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human 116 kDa U5 small nuclear ribonucleoprotein component protein (1-205AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q15029 |
Uniprot Id
Q15029
Target Species
Human
Target Name
EFTUD2
Target Full Name
116 kDa U5 small nuclear ribonucleoprotein component
Target Function
Required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Component of the U5 snRNP and the U4/U6-U5 tri-snRNP complex, a building block of the spliceosome.
Target Involvement
Mandibulofacial dysostosis with microcephaly (MFDM)
Target Subcellular Location
Nucleus.
Target Protein Families
TRAFAC class translation factor GTPase superfamily, Classic translation factor GTPase family, EF-G/EF-2 subfamily
Target Synonyms
116 kDa; 116 kDa U5 small nuclear ribonucleoprotein component; EFTUD2; Elongation factor Tu GTP binding domain containing 2; Elongation factor Tu GTP-binding domain-containing protein 2; hSNU114; MFDGA; MFDM; SNRNP116; Snrp116; Snu114; SNU114 homolog; U5 116KD; U5 small nuclear ribonucleoprotein component; U5 snRNP specific protein, 116 kD; U5 snRNP specific protein, 116 kDa; U5 snRNP-specific protein; U5-116 kDa; U5-116KD; U5S1_HUMAN
Target Background
This gene encodes a GTPase which is a component of the spliceosome complex which processes precursor mRNAs to produce mature mRNAs. Mutations in this gene are associated with mandibulofacial dysostosis with microcephaly. Multiple transcript variants encoding different isoforms have been found for this gene.
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