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Rabbit anti-Human EGR4 Polyclonal Antibody

The antibody against EGR4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_001956.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-09838A

The antibody against EGR4 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_001956.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-09838A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEGR4
Target SynonymsAT133; NGFIC; NGFI-C; PAT133; EGR4FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.01% thimerosal, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse brainApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 440-589 of human EGR4 (NP_001956.3).Target SpeciesHuman
Immunogen SequenceGVAAPPVPPPPPTPFPQAKARRKGRRGGKCSTRCFCPRPHAKAFACPVESCVRSFARSDELNRHLRIHTGHKPFQCRICLRNFSRSDHLTTHVRTHTGEKPFACDVCGRRFARSDEKKRHSKVHLKQKARAEERLKGLGFYSLGLSFASLUniprot IDQ05215
Background Information
  • Uniprot Id

    Q05215

  • Target Species

    Human

  • Target Name

    EGR4

  • Target Full Name

    Early growth response protein 4

  • Target Function

    Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCGGGGGCG-3' (GSG). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.

  • Target Subcellular Location

    Nucleus.

  • Target Protein Families

    EGR C2H2-type zinc-finger protein family

  • Target Synonyms

    NGFIC; NGF1-C; NGFI-C; pAT133; Egr4

  • Target Background

    Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in several structures, including central nervous system; genitourinary system; and tooth. Orthologous to human EGR4 (early growth response 4).

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