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The antibody against EIF4G3 was raised in rabbit using the Human EIF4G3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against EIF4G3 was raised in rabbit using the Human EIF4G3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$600.00
| Cat.No | ADC-48652A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EIF4G3 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Human EIF4G3 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O43432 |
Uniprot Id
O43432
Target Species
Human
Target Name
EIF4G3
Target Full Name
Eukaryotic translation initiation factor 4 gamma 3
Target Function
Probable component of the protein complex eIF4F, which is involved in the recognition of the mRNA cap, ATP-dependent unwinding of 5'-terminal secondary structure and recruitment of mRNA to the ribosome. Thought to be a functional homolog of EIF4G1.
Target Protein Families
Eukaryotic initiation factor 4G family
Target Synonyms
eIF-4-gamma 3; eIF-4-gamma II; eIF-4G 3; eIF4G 3; EIF4G3; eIF4GII; Eukaryotic translation initiation factor 4 gamma 3; eukaryotic translation initiation factor 4 gamma; 3; eukaryotic translation initiation factor-4 gamma; 3; IF4G3_HUMAN
Target Background
The protein encoded by this gene is thought to be part of the eIF4F protein complex, which is involved in mRNA cap recognition and transport of mRNAs to the ribosome. Interestingly, a microRNA (miR-520c-3p) has been found that negatively regulates synthesis of the encoded protein, and this leads to a global decrease in protein translation and cell proliferation. Therefore, this protein is a key component of the anti-tumor activity of miR-520c-3p.
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