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The antibody against EIF5A2 was raised in rabbit using the Recombinant Human Eukaryotic translation initiation factor 5A-2 protein (2-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against EIF5A2 was raised in rabbit using the Recombinant Human Eukaryotic translation initiation factor 5A-2 protein (2-153AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
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Immunohistochemistry of paraffin-embedded human testis tissue using EIF5A2 Antibody at dilution of 1:100
Immunofluorescent analysis of Hela cells using EIF5A2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-18229A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EIF5A2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Eukaryotic translation initiation factor 5A-2 protein (2-153AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZV4 |
Uniprot Id
Q9GZV4
Target Species
Human
Target Name
EIF5A2
Target Full Name
Eukaryotic translation initiation factor 5A-2
Target Function
mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. Functions as a regulator of apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation.
Target Subcellular Location
Cytoplasm. Nucleus. Endoplasmic reticulum membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus, nuclear pore complex.
Target Protein Families
EIF-5A family
Target Tissue Specificity
Expressed in ovarian and colorectal cancer cell lines (at protein level). Highly expressed in testis. Overexpressed in some cancer cells.
Target Synonyms
9630038B20; eIF 5A 2; eIF 5A2; eIF-4D; eIF-5A-2; eIF-5A2; EIF5A 2; EIF5A2; eIF5AII; Eukaryotic initiation factor 5A isoform 2; Eukaryotic translation initiation factor 5A-2; Eukaryotic translation initiation factor 5A2; IF5A2_HUMAN
Target Background
Predicted to enable translation elongation factor activity. Predicted to be involved in positive regulation of translational elongation. Located in intracellular membrane-bounded organelle.
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