Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against ELMO2 was raised in rabbit using the Recombinant Human Engulfment and cell motility protein 2 protein (304-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against ELMO2 was raised in rabbit using the Recombinant Human Engulfment and cell motility protein 2 protein (304-371AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
$299.00
Immunohistochemistry of paraffin-embedded human placenta tissue using ELMO2 Antibody at dilution of 1:100
Immunofluorescent analysis of A549 cells using ELMO2 Antibody at dilution of 1:100 and Alexa Fluor 488-congugated AffiniPure Goat Anti-Rabbit IgG(H+L)2
| Cat.No | ADC-10251A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELMO2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Engulfment and cell motility protein 2 protein (304-371AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q96JJ3 |
Uniprot Id
Q96JJ3
Target Species
Human
Target Name
ELMO2
Target Full Name
Engulfment and cell motility protein 2
Target Function
Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in association with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Target Involvement
Vascular malformation, primary intraosseous (VMOS)
Target Subcellular Location
Cytoplasm. Cytoplasm, cytosol. Membrane.
Target Tissue Specificity
Widely expressed, with a higher expression in skeletal muscle, kidney and placenta.
Target Synonyms
CED 12; Ced 12 homolog 2; CED 12 homolog A; CED 12A; CED-12; ced-12 homolog 2; CED12; CED12 homolog A; CED12; C. elegans; homolog of; 2; CED12A; ELMO 2; ELMO-2; ELMO2; ELMO2_HUMAN; Engulfment and cell motility 2 (ced 12 homolog; C. elegans); Engulfment and cell motility 2; Engulfment and cell motility gene 2; Engulfment and cell motility protein 2; FLJ11656; hCED 12A; hCED-12A; hCED12A; KIAA1834; OTTHUMP00000031762; PH domain protein CED12A; Protein ced 12 homolog A; Protein ced-12 homolog A
Target Background
The protein encoded by this gene interacts with the dedicator of cyto-kinesis 1 protein. Similarity to a C. elegans protein suggests that this protein may function in phagocytosis of apoptotic cells and in cell migration. Alternative splicing results in multiple transcript variants.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
