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Rabbit anti-Human ELMOD3 Polyclonal Antibody, FITC conjugated

The antibody against ELMOD3 was raised in rabbit using the Recombinant Human ELMO domain-containing protein 3 protein (1-102AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

ADC-05549A

The antibody against ELMOD3 was raised in rabbit using the Recombinant Human ELMO domain-containing protein 3 protein (1-102AA) as the immunogen. This antibody exists as a fitc conjugated isotype IgG, purified by protein G with a purity greater than 95%.

$299.00

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Specifications


Cat.No ADC-05549A ClonalityPolyclonal
Host SpeciesRabbitTarget NameELMOD3
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4
Purification Method>95%, Protein G purifiedConjugateFITC conjugated
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human ELMO domain-containing protein 3 protein (1-102AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ96FG2
Background Information
  • Uniprot Id

    Q96FG2

  • Target Species

    Human

  • Target Name

    ELMOD3

  • Target Full Name

    ELMO domain-containing protein 3

  • Target Function

    Acts as a GTPase-activating protein (GAP) for ARL2 with low specific activity.

  • Target Involvement

    Deafness, autosomal recessive, 88 (DFNB88)

  • Target Subcellular Location

    Cell projection, stereocilium. Cell projection, kinocilium. Cytoplasm, cytoskeleton.

  • Target Tissue Specificity

    Both isoform 1 and isoform 6 are widely expressed.

  • Target Synonyms

    ELMOD3; RBED1; RBM29; PP4068ELMO domain-containing protein 3; RNA-binding motif and ELMO domain-containing protein 1; RNA-binding motif protein 29; RNA-binding protein 29

  • Target Background

    This gene encodes a member of the engulfment and cell motility family of GTPase-activating proteins that regulate Arf GTPase proteins. Members of this family are defined by a conserved engulfment and cell motility domain. In rat cochlea, the encoded protein is found in stereocilia, kinocilia and cuticular plate of developing hair cells suggesting a function for this protein in cochlear sensory cells. An allelic variant of this family has been associated with autosomal recessive nonsyndromic deafness-88 in humans. Alternative splicing results in multiple transcript variants.

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