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The antibody against ELOVL1 was raised in rabbit using the Synthesized peptide derived from internal of Human ELOVL1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against ELOVL1 was raised in rabbit using the Synthesized peptide derived from internal of Human ELOVL1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
$297.00
Western blot analysis of extracts from HepG2 cells and Jurkat cells, using ELOVL1 antibody.
| Cat.No | ADC-41250A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELOVL1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ELOVL1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BW60 |
Uniprot Id
Q9BW60
Target Species
Human
Target Name
ELOVL1
Target Full Name
Very long chain fatty acid elongase 1
Target Function
Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that exhibits activity toward saturated and monounsaturated acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Target Subcellular Location
Endoplasmic reticulum membrane; Multi-pass membrane protein.
Target Protein Families
ELO family, ELOVL1 subfamily
Target Tissue Specificity
Ubiquitous.
Target Synonyms
ELOVL1; SSC1; CGI-88; Elongation of very long chain fatty acids protein 1; 3-keto acyl-CoA synthase ELOVL1; ELOVL fatty acid elongase 1; ELOVL FA elongase 1; Very long chain 3-ketoacyl-CoA synthase 1; Very long chain 3-oxoacyl-CoA synthase 1
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