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The antibody against ELP2 was raised in rabbit using the Recombinant Human Elongator complex protein 2 protein (323-457AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
The antibody against ELP2 was raised in rabbit using the Recombinant Human Elongator complex protein 2 protein (323-457AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC, IF.
$299.00
| Cat.No | ADC-04845A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ELP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Elongator complex protein 2 protein (323-457AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6IA86 |
Uniprot Id
Q6IA86
Target Species
Human
Target Name
ELP2
Target Full Name
Elongator complex protein 2
Target Function
Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. The elongator complex catalyzes formation of carboxymethyluridine in the wobble base at position 34 in tRNAs.
Target Involvement
Mental retardation, autosomal recessive 58 (MRT58)
Target Subcellular Location
Cytoplasm. Nucleus.
Target Protein Families
WD repeat ELP2 family
Target Synonyms
AU023723 ; Elongation protein 2 homolog (S. cerevisiae); Elongator acetyltransferase complex subunit 2; Elongator complex protein 2; elongator protein 2; ELP2; ELP2_HUMAN; Epl2; FLJ10879 ; SHINC 2; SHINC-2; SHINC2; signal transducer and activator of transcription 3 interacting protein 1; signal transducer and activator of transcription interacting protein 1; STAT3 interacting protein 1; Stat3 interacting protein; STAT3-interacting protein 1; STATIP 1; STATIP1; STATIP1 protein ; StIP; StIP1
Target Background
The protein encoded by this gene is a core subunit of the elongator complex, a histone acetyltransferase complex that associates with RNA polymerase II. In addition to histone acetylation, the encoded protein effects transcriptional elongation and may help remodel chromatin.
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