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The antibody against ENO2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 195-434 of human ENO2 (NP_001966.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.
The antibody against ENO2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 195-434 of human ENO2 (NP_001966.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.
| Cat.No | ADA-11761A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ENO2 |
| Target Synonyms | NSE; HEL-S-279; ENO2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain, SH-SY5Y | Application | ELISA, WB, IF/ICC, IP |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 195-434 of human ENO2 (NP_001966.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P09104 | Immunogen Sequence |
Uniprot Id
P09104
Target Species
Human
Target Name
ENO2
Target Full Name
Gamma-enolase
Target Function
Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival.
Target Subcellular Location
Cytoplasm. Cell membrane.
Target Protein Families
Enolase family
Target Tissue Specificity
The alpha/alpha homodimer is expressed in embryo and in most adult tissues. The alpha/beta heterodimer and the beta/beta homodimer are found in striated muscle, and the alpha/gamma heterodimer and the gamma/gamma homodimer in neurons.
Target Synonyms
NSE; HEL-S-279; ENO2
Target Background
This gene encodes one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.
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