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The antibody against ENTPD6 was raised in rabbit using the Human ENTPD6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against ENTPD6 was raised in rabbit using the Human ENTPD6 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48635A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ENTPD6 |
| Target Synonyms | ENTPD6; CD39L2; IL6ST2; Ectonucleoside triphosphate diphosphohydrolase 6; NTPDase 6; CD39 antigen-like 2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human ENTPD6 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | O75354 |
Uniprot Id
O75354
Target Species
Human
Target Name
ENTPD6
Target Full Name
Ectonucleoside triphosphate diphosphohydrolase 6
Target Function
Catalyzes the hydrolysis of nucleoside triphosphates and diphosphates in a calcium- or magnesium-dependent manner. Has a strong preference for nucleoside diphosphates, preferentially hydrolyzes GDP, IDP, and UDP, with slower hydrolysis of CDP, ITP, GTP, CTP, ADP, and UTP and virtually no hydrolysis of ATP. The membrane bound form might support glycosylation reactions in the Golgi apparatus and, when released from cells, might catalyze the hydrolysis of extracellular nucleotides.
Target Subcellular Location
Golgi apparatus membrane; Single-pass type II membrane protein. Secreted. Cell membrane; Single-pass type II membrane protein.
Target Protein Families
GDA1/CD39 NTPase family
Target Tissue Specificity
Expressed in most tissues, but predominantly in heart.
Target Synonyms
ENTPD6; CD39L2; IL6ST2; Ectonucleoside triphosphate diphosphohydrolase 6; NTPDase 6; CD39 antigen-like 2
Target Background
ENTPD6 is similar to E-type nucleotidases (NTPases). NTPases, such as CD39, mediate catabolism of extracellular nucleotides. ENTPD6 contains 4 apyrase-conserved regions which are characteristic of NTPases. Alternative splicing results in multiple transcript variants encoding different isoforms.
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