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The antibody against EPB41L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human EPB41L2 (NP_001186317.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against EPB41L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human EPB41L2 (NP_001186317.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-01048A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPB41L2 |
| Target Synonyms | 4.1G; 4.1-G; EPB41L2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Jurkat, SKOV3, U-87MG | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-210 of human EPB41L2 (NP_001186317.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O43491 | Immunogen Sequence |
Uniprot Id
O43491
Target Species
Human
Target Name
EPB41L2
Target Full Name
Band 4.1-like protein 2
Target Function
Required for dynein-dynactin complex and NUMA1 recruitment at the mitotic cell cortex during anaphase.
Target Subcellular Location
Cytoplasm, cytoskeleton. Cytoplasm, cell cortex. Cell membrane.
Target Tissue Specificity
Widely expressed.
Target Synonyms
4.1 G ; 4.1G; AW555191; Band 4.1 like protein 2 ; Band 4.1-like protein 2; D10Ertd398e; DKFZp781D1972; DKFZp781H1755; E41L2_HUMAN; Epb41l2; Erythrocyte membrane protein band 4.1 like 2; Erythrocyte membrane protein band 4.1 like protein 2; Generally expressed protein 4.1; NBL2; OTTHUMP00000017197; OTTHUMP00000040262
Target Background
Predicted to enable PH domain binding activity; cytoskeletal protein binding activity; and structural molecule activity. Involved in positive regulation of protein localization to cell cortex. Located in cell junction; nucleoplasm; and plasma membrane. Colocalizes with COP9 signalosome.
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