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The antibody against EPS15L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against EPS15L1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-01920A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPS15L1 |
| Target Synonyms | EPS15R; EPS15L1 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, BxPC-3, HepG2, MCF7, U-251MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 475-754 of human EPS15L1 (NP_001245304.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UBC2 | Immunogen Sequence |
Uniprot Id
Q9UBC2
Target Species
Human
Target Name
EPS15L1
Target Full Name
Epidermal growth factor receptor substrate 15-like 1
Target Function
Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.
Target Subcellular Location
Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit.
Target Synonyms
EP15R_HUMAN; epidermal growth factor receptor pathway substrate 15- ike 1; Epidermal growth factor receptor substrate 15 like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15 related protein; Eps15-related protein; EPS15L1; Eps15R
Target Background
Enables cadherin binding activity. Predicted to be involved in endocytosis and endosomal transport. Located in membrane.
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