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Rabbit anti-Human EPS15L1 Polyclonal Antibody

The antibody against EPS15L1 was raised in rabbit using the Fusion protein of Human EPS15L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-30769A

The antibody against EPS15L1 was raised in rabbit using the Fusion protein of Human EPS15L1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-30769A ClonalityPolyclonal
Host SpeciesRabbitTarget NameEPS15L1
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human EPS15L1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9UBC2
Background Information
  • Uniprot Id

    Q9UBC2

  • Target Species

    Human

  • Target Name

    EPS15L1

  • Target Full Name

    Epidermal growth factor receptor substrate 15-like 1

  • Target Function

    Seems to be a constitutive component of clathrin-coated pits that is required for receptor-mediated endocytosis. Involved in endocytosis of integrin beta-1 (ITGB1) and transferrin receptor (TFR); internalization of ITGB1 as DAB2-dependent cargo but not TFR seems to require association with DAB2.

  • Target Subcellular Location

    Cell membrane; Peripheral membrane protein. Nucleus. Membrane, coated pit.

  • Target Synonyms

    EP15R_HUMAN; epidermal growth factor receptor pathway substrate 15- ike 1; Epidermal growth factor receptor substrate 15 like 1; Epidermal growth factor receptor substrate 15-like 1; epidermal growth factor receptor substrate EPS15R; Eps15 related protein; Eps15-related protein; EPS15L1; Eps15R

  • Target Background

    Enables cadherin binding activity. Predicted to be involved in endocytosis and endosomal transport. Located in membrane.

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