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The antibody against EPS8L2 was raised in rabbit using the Recombinant Human Epidermal growth factor receptor kinase substrate 8-like protein 2 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against EPS8L2 was raised in rabbit using the Recombinant Human Epidermal growth factor receptor kinase substrate 8-like protein 2 protein (201-500AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human kidney tissue using EPS8L2 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human skin tissue using EPS8L2 Antibody at dilution of 1:1002
| Cat.No | ADC-17857A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPS8L2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Epidermal growth factor receptor kinase substrate 8-like protein 2 protein (201-500AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6S3 |
Uniprot Id
Q9H6S3
Target Species
Human
Target Name
EPS8L2
Target Full Name
Epidermal growth factor receptor kinase substrate 8-like protein 2
Target Function
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells.
Target Involvement
Deafness, autosomal recessive, 106 (DFNB106)
Target Subcellular Location
Cytoplasm. Cell projection, stereocilium.
Target Protein Families
EPS8 family
Target Tissue Specificity
Detected in fibroblasts and placenta.
Target Synonyms
Epidermal growth factor receptor kinase substrate 8 like protein 2; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8 like protein 2; Epidermal growth factor receptor pathway substrate 8 related protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8 like 2; EPS8 like protein 2; EPS8 related protein 2; EPS8-like protein 2; EPS8-related protein 2; EPS8L 2; EPS8L2; EPS8R 2; EPS8R2; ES8L2_HUMAN; FLJ16738; FLJ21935; FLJ22171; MGC126530; MGC3088
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