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The antibody against EPS8L2 was raised in rabbit using the Synthesized peptide derived from internal of Human ES8L2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against EPS8L2 was raised in rabbit using the Synthesized peptide derived from internal of Human ES8L2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from HeLa cells, Jurkat cells and HUVEC cells, using ES8L2 antibody.
| Cat.No | ADC-41802A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | EPS8L2 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human ES8L2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9H6S3 |
Uniprot Id
Q9H6S3
Target Species
Human
Target Name
EPS8L2
Target Full Name
Epidermal growth factor receptor kinase substrate 8-like protein 2
Target Function
Stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells.
Target Involvement
Deafness, autosomal recessive, 106 (DFNB106)
Target Subcellular Location
Cytoplasm. Cell projection, stereocilium.
Target Protein Families
EPS8 family
Target Tissue Specificity
Detected in fibroblasts and placenta.
Target Synonyms
Epidermal growth factor receptor kinase substrate 8 like protein 2; Epidermal growth factor receptor kinase substrate 8-like protein 2; Epidermal growth factor receptor pathway substrate 8 like protein 2; Epidermal growth factor receptor pathway substrate 8 related protein 2; Epidermal growth factor receptor pathway substrate 8-related protein 2; EPS8 like 2; EPS8 like protein 2; EPS8 related protein 2; EPS8-like protein 2; EPS8-related protein 2; EPS8L 2; EPS8L2; EPS8R 2; EPS8R2; ES8L2_HUMAN; FLJ16738; FLJ21935; FLJ22171; MGC126530; MGC3088
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