Rabbit anti-Human ERBB2IP Polyclonal Antibody

The antibody against ERBB2IP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01161A

Number

Cat.No	ADA-01161A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	ERBB2IP
Target Synonyms	LAP2; ERBB2IP; HEL-S-78	Form	Liquid
Species Reactivity	Human	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	293T, HepG2	Application	ELISA, WB

Cat.No

ADA-01161A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

ERBB2IP

Target Synonyms

LAP2; ERBB2IP; HEL-S-78

Form

Liquid

Species Reactivity

Human

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

293T, HepG2

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1).	Target Species	Human
Uniprot ID	Q96RT1	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1152-1371 of human ERBB2IP (NP_061165.1).

Target Species

Human

Uniprot ID

Q96RT1

Immunogen Sequence

Background Information

Uniprot Id

Q96RT1
Target Species

Human
Target Name

ERBIN
Target Full Name

Erbin
Target Function

Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state. Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion.
Target Subcellular Location

Cell junction, hemidesmosome. Nucleus membrane. Basolateral cell membrane.
Target Protein Families

LAP (LRR and PDZ) protein family
Target Tissue Specificity

Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine.
Target Synonyms

Densin-180-like protein; Erbb2-interacting protein; Erbb2ip; Erbin; LAP2; LAP2_HUMAN; Protein LAP2
Target Background

This gene is a member of the leucine-rich repeat and PDZ domain (LAP) family. The encoded protein contains 17 leucine-rich repeats and one PDZ domain. It binds to the unphosphorylated form of the ERBB2 protein and regulates ERBB2 function and localization. It has also been shown to affect the Ras signaling pathway by disrupting Ras-Raf interaction. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Rabbit anti-Human ERBB2IP Polyclonal Antibody

Specifications

Immunogen Information

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