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The antibody against ERC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 770-850 of human ERC2 (NP_056391.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against ERC2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 770-850 of human ERC2 (NP_056391.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-04821A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ERC2 |
| Target Synonyms | CAST; CAST1; ELKSL; Spc110; SPBC110; ERC2 | Form | Liquid |
| Species Reactivity | Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, Mouse brain | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 770-850 of human ERC2 (NP_056391.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | HNQQLEKKKNAQLLEEVRRREDSMADNSQHLQIEELMNALEKTRQELDATKARLASTQQSLAEKEAHLANLRIERRKQLEE | Uniprot ID | O15083 |
Uniprot Id
O15083
Target Species
Human
Target Name
ERC2
Target Full Name
ERC protein 2
Target Function
Thought to be involved in the organization of the cytomatrix at the nerve terminals active zone (CAZ) which regulates neurotransmitter release. Seems to act together with BSN. May recruit liprin-alpha proteins to the CAZ.
Target Subcellular Location
Cytoplasm. Cell junction, synapse. Cell junction, synapse, presynaptic active zone. Cytoplasm, cytoskeleton.
Target Synonyms
Cast; CAST1; CAZ-associated structural protein 1; Cmbp (gene name); Cytomatrix protein p110; ERC protein 2; Erc2; ERC2_HUMAN; KIAA0378
Target Background
This gene encodes a protein that belongs to the Rab3-interacting molecule (RIM)-binding protein family. Members of this protein family form part of the cytomatrix at the active zone (CAZ) complex and function as regulators of neurotransmitter release. Alternative splicing results in multiple transcript variants.
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