Chinese (Simplified)
English
German
Korean
Spanish
Sign up for an account to enjoy easy online shopping and instant order tracking.
The antibody against ERCC6L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against ERCC6L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03461A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | ERCC6L2 |
| Target Synonyms | HEBO; BMFS2; SR278; RAD26L; C9orf102; ERCC6L2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse kidney, LO2, MCF-7, Mouse testis, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1262-1561 of human ERCC6L2 (NP_064592.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q5T890 | Immunogen Sequence |
Uniprot Id
Q5T890
Target Species
Human
Target Name
ERCC6L2
Target Full Name
DNA excision repair protein ERCC-6-like 2
Target Function
May be involved in early DNA damage response.
Target Involvement
Bone marrow failure syndrome 2 (BMFS2)
Target Subcellular Location
Nucleus. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Mitochondrion. Note=Colocalizes with NEK6 in the centrosome. In response to DNA damage, translocates from the cytosol to mitochondria and nucleus in a reactive oxygen species (ROS)-dependent manner.
Target Protein Families
SNF2/RAD54 helicase family
Target Tissue Specificity
Expressed in bone marrow (at protein level).
Target Synonyms
C9orf102; Chromosome 9 open reading frame 102; excision repair cross-complementing rodent repair deficiency; complementation group 6-like 2; FLJ37706; MGC30192; MGC43364; Putative DNA repair and recombination protein RAD26-like; putative repair and recombination helicase RAD26L; RAD26_HUMAN; Rad26l; RAD26L hypothetical protein; SR278; stretch responsive protein 278
Target Background
This gene encodes a member of the Snf2 family of helicase-like proteins. The encoded protein may play a role in DNA repair and mitochondrial function. Mutations in this gene have been associated with bone marrow failure syndrome 2. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Free shipping on orders $999+
Advenit post multos Scudilo Scutariorum tribunus velament
We accept credit cards, PayPal, and bank wires
Responsive and knowledgable customer service via email, text or phone
Notification
